Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 18/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 13/20 | 0.60 |
| ▸ | NCOR2 | Q9Y618 | 8/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.60 |
| ▸ | TET3 | O43151 | 1/20 | 0.60 |
| ▸ | BRD4 | O60885 | 1/20 | 0.60 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.60 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.60 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.60 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14449045 | 0.81 | HDAC1 (0.62) | HDAC1HDAC2HDAC3NCOR2HDAC6 | |
| SCHEMBL4553069 | 0.81 | HDAC1 (0.59) | HDAC1HDAC2HDAC3HDAC6HDAC8 | |
| SCHEMBL4433358 | 0.79 | HDAC1 (0.58) | HDAC1HDAC6HDAC8 | |
| SCHEMBL1885467 | 0.79 | HDAC1 (0.65) | HDAC1HDAC2HDAC3NCOR2HDAC6 | |
| SCHEMBL20232415 | 0.78 | HDAC1 (0.69) | HDAC1HDAC2HDAC3NCOR2HDAC6 | |
| SCHEMBL18414708 | 0.76 | HDAC1 (0.66) | HDAC1HDAC2HDAC3NCOR2HDAC6 | |
| Panobinostat SCHEMBL164801 | 0.75 | HDAC1 (1.00) | HDAC1HDAC2HDAC3NCOR2HDAC6 | |
| Panobinostat SCHEMBL22773814 | 0.75 | HDAC1 (1.00) | HDAC1HDAC2HDAC3NCOR2HDAC6 | |
| Panobinostat SCHEMBL183197 | 0.75 | HDAC1 (1.00) | HDAC1HDAC2HDAC3NCOR2HDAC6 | |
| Panobinostat SCHEMBL436875 | 0.75 | HDAC1 (0.98) | HDAC1HDAC2HDAC3NCOR2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167499-A1 | Biaryl linked hydroxamates: preparation and pharmaceutical applications | A*BIO PTE LTD. (SG) | 2007-07-19 | — | — | US | disclosed |
| US-20070167499-A1 | Biaryl linked hydroxamates: preparation and pharmaceutical applications | A*BIO PTE LTD. (SG) | 2007-07-19 | — | — | US | disclosed |
| WO-2005040161-A1 | BIARYL LINKED HYDROXAMATES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167499-A1 | Biaryl linked hydroxamates: preparation and pharmaceutical applications | HDAC1, HDAC11, HDAC2 | HDAC1 1/4885HDAC2 3/4885HDAC3 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.