SCHEMBL82889

SCHEMBL82889

F[C@@H]1[CH]C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL322524 1.00
SCHEMBL6525353 0.91
SCHEMBL387641 0.67
SCHEMBL477777 0.63
SCHEMBL3041141 0.60
SCHEMBL775882 0.60
SCHEMBL14890300 0.60
SCHEMBL38170 0.56
SCHEMBL6359505 0.56
SCHEMBL16617782 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166078-A 2-oxoquinazoline derivatives as methionine adenosyltransferase 2A inhibitors 伊迪亚生物科学有限公司 2021-07-23 CN claimed
CN-107428762-B Phthalazinone derivatives, preparation method and use thereof 四川科伦博泰生物医药股份有限公司 2020-03-10 CN claimed
EP-2352723-B1 PESTICIDAL N-ARYL- OR N-HETEROARYL PYRAZOLE CARBOXAMIDE COMPOUNDS BAYER IP GMBH (DE) 2016-11-23 EP claimed
US-20020193591-A1 Process for producing 5-amino-8-alkylquinolonecarboxylic acid derivative and intermediates in the production thereof DAIICHI PHARMACEUTICAL CO., LTD. 2002-12-19 US claimed
EP-1167344-A1 PROCESS FOR PRODUCING 5-AMINO-8- ALKYLQUINOLO NECARBOXYLIC ACID DERIVATIVES AND INTERMEDIATES IN THE PRODUCTION THEREOF DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2002-01-02 EP claimed
US-20240173326-A1 COMBINATION THERAPY COMPRISING A MAT2A INHIBITOR AND A TYPE II PRMT INHIBITOR IDEAYA BIOSCIENCES, INC. 2024-05-30 US disclosed
EP-4351570-A1 COMBINATION THERAPY COMPRISING A MAT2A INHIBITOR AND TYPE I PRMT INHIBITOR Ideaya Biosciences, Inc. (US) 2024-04-17 EP disclosed
EP-4347569-A1 COMBINATION THERAPY COMPRISING A MAT2A INHIBITOR AND A TYPE II PRMT INHIBITOR Ideaya Biosciences, Inc. (US) 2024-04-10 EP disclosed
US-20240108626-A1 COMBINATION THERAPY COMPRISING A MAT2A INHIBITOR AND A TYPE II PRMT INHIBITOR IDEAYA BIOSCIENCES, INC. 2024-04-04 US disclosed
WO-2023086934-A1 COMBINATION THERAPY COMPRISING A MAT2A INHIBITOR AND A TAXANE IDEAYA BIOSCIENCES, INC. (US) 2023-05-19 WO disclosed
US-20230087118-A1 IMIDAZO[1,2-a]PYRIDINYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE BIOGEN MA INC. 2023-03-23 US disclosed
WO-2022256808-A1 COMBINATION THERAPY COMPRISING A MAT2A INHIBITOR AND TYPE I PRMT INHIBITOR IDEAYA BIOSCIENCES INC. (US) 2022-12-08 WO disclosed
EP-1930006-A1 METHOD FOR PRODUCTION OF QUINOLONE-CONTAINING LYOPHILIZED PREPARATION Daiichi Sankyo Company, Limited (JP) 2008-06-11 EP disclosed
EP-1134219-B1 CYCLOALKYL-SUBSTITUTED AMINOMETHYLPYRROLIDINE DERIVATIVES DAIICHI SEIYAKU CO (JP) 2005-06-15 EP disclosed
CN-1173971-C Cycloalkyl-substituted aminomethylpyrrolidine derivatives ��һ��������ҩ��ʽ���� 2004-11-03 CN disclosed
US-6573260-B1 Antibiotics DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-06-03 US disclosed
US-20020193591-A1 Process for producing 5-amino-8-alkylquinolonecarboxylic acid derivative and intermediates in the production thereof DAIICHI PHARMACEUTICAL CO., LTD. 2002-12-19 US disclosed
CN-1333765-A cycloalkyl-substituted aminomethyl pyrrolidine derivatives DAIICHI SEIYAKU CO (JP) 2002-01-30 CN disclosed
EP-1167344-A1 PROCESS FOR PRODUCING 5-AMINO-8- ALKYLQUINOLO NECARBOXYLIC ACID DERIVATIVES AND INTERMEDIATES IN THE PRODUCTION THEREOF DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2002-01-02 EP disclosed
EP-1134219-A1 CYCLOALKYL-SUBSTITUTED AMINOMETHYLPYRROLIDINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-09-19 EP disclosed