Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289799 | 0.91 | GRIA2 (0.64) | GRIA2GRIA4 | |
| SCHEMBL8289356 | 0.90 | GRIA2 (0.62) | GRIA2GRIA4 | |
| SCHEMBL8289352 | 0.89 | GRIA2 (0.80) | GRIA2GRIA4 | |
| SCHEMBL8289355 | 0.89 | GRIA2 (0.79) | GRIA2GRIA4 | |
| SCHEMBL8289341 | 0.88 | GRIA2 (0.77) | GRIA2GRIA4 | |
| SCHEMBL4372732 | 0.88 | GRIA4 (0.76) | GRIA2GRIA4 | |
| SCHEMBL8289798 | 0.87 | GRIA4 (0.78) | GRIA2GRIA4 | |
| SCHEMBL8289348 | 0.87 | GRIA2 (0.64) | GRIA2GRIA4 | |
| SCHEMBL8288316 | 0.87 | GRIA2 (0.78) | GRIA2GRIA4 | |
| SCHEMBL8287335 | 0.86 | GRIA2 (0.60) | GRIA2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670757-B1 | PYRROLE AND PYRAZOLE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | LILLY CO ELI (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2005040110-A1 | PYRROLE AND PYRAZOLE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2005-05-06 | — | — | WO | disclosed |