Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 14/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.60 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369012 | 0.86 | HDAC1 (0.84) | HDAC1HDAC8HDAC6HDAC2HDAC11 | |
| SCHEMBL3369008 | 0.86 | HDAC1 (0.84) | HDAC1HDAC8HDAC6HDAC2HDAC11 | |
| SCHEMBL3366912 | 0.80 | HDAC1 (0.64) | HDAC1HDAC8HDAC6HDAC2HDAC11 | |
| SCHEMBL8324416 | 0.79 | HDAC1 (0.70) | HDAC1HDAC8HDAC6HDAC2HDAC11 | |
| SCHEMBL8289428 | 0.78 | HDAC1 (0.85) | HDAC1HDAC8HDAC6HDAC2HDAC11 | |
| SCHEMBL13118182 | 0.77 | HDAC1 (0.86) | HDAC1HDAC8HDAC6HDAC2HDAC11 | |
| SCHEMBL8291156 | 0.77 | HDAC1 (0.56) | HDAC1HDAC8HDAC6HDAC2HDAC11 | |
| SCHEMBL6507256 | 0.77 | HDAC1 (0.73) | HDAC1HDAC8HDAC6HDAC2HDAC11 | |
| SCHEMBL6513450 | 0.77 | HDAC1 (0.73) | HDAC1HDAC8HDAC6HDAC2HDAC11 | |
| SCHEMBL8320549 | 0.76 | HDAC1 (0.70) | HDAC1HDAC8HDAC6HDAC2HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005028447-A1 | BENZIMIDAZOLE DERIVATES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2005-03-31 | — | — | WO | disclosed |