Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 18/20 | 0.54 |
| ▸ | GRIA4 | P48058 | 18/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289785 | 0.92 | GRIA2 (0.60) | GRIA2GRIA4 | |
| SCHEMBL8289872 | 0.90 | GRIA4 (0.69) | GRIA2GRIA4 | |
| SCHEMBL8289333 | 0.88 | GRIA2 (0.57) | GRIA2GRIA4KDM4EMEN1ALDH1A1 | |
| SCHEMBL4373295 | 0.88 | GRIA2 (0.59) | GRIA2GRIA4 | |
| SCHEMBL8288315 | 0.87 | GRIA2 (0.64) | GRIA2GRIA4 | |
| SCHEMBL13863270 | 0.84 | GRIA2 (0.66) | GRIA2GRIA4KDM4EMEN1ALDH1A1 | |
| SCHEMBL4482679 | 0.84 | GRIA2 (0.56) | GRIA2GRIA4 | |
| SCHEMBL8288317 | 0.84 | GRIA2 (0.75) | GRIA2GRIA4 | |
| SCHEMBL8289784 | 0.83 | GRIA2 (0.60) | GRIA2GRIA4KDM4EMEN1ALDH1A1 | |
| SCHEMBL4373418 | 0.82 | GRIA2 (0.56) | GRIA2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040110-A1 | PYRROLE AND PYRAZOLE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2005-05-06 | — | — | WO | disclosed |