Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 17/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 15/20 | 0.43 |
| ▸ | F11 | P03951 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289845 | 0.87 | GRIA4 (0.57) | GRIA4GRIA2 | |
| SCHEMBL13612281 | 0.86 | GRIA4 (0.48) | GRIA4GRIA2F11 | |
| SCHEMBL8287453 | 0.82 | GRIA4 (0.61) | GRIA4GRIA2 | |
| SCHEMBL8289600 | 0.81 | GRIA4 (0.45) | GRIA4GRIA2 | |
| SCHEMBL8289427 | 0.81 | GRIA4 (0.47) | GRIA4GRIA2F11 | |
| SCHEMBL8289543 | 0.81 | GRIA4 (0.40) | GRIA4GRIA2F11 | |
| SCHEMBL8289552 | 0.80 | GRIA4 (0.46) | GRIA4GRIA2 | |
| SCHEMBL8289444 | 0.80 | GRIA4 (0.41) | GRIA4GRIA2 | |
| SCHEMBL8288468 | 0.80 | GRIA4 (0.50) | GRIA4GRIA2 | |
| SCHEMBL8289441 | 0.80 | GRIA4 (0.58) | GRIA4GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040110-A1 | PYRROLE AND PYRAZOLE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2005-05-06 | — | — | WO | disclosed |