Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 6/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.59 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.56 |
| ▸ | ITGAM | P11215 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3894018 | 0.90 | MAP3K5 (0.79) | MAP3K5MAPTAPEX1ITGB2ITGAM | |
| SCHEMBL13056334 | 0.90 | MAP3K5 (0.79) | MAP3K5MAPTAPEX1ITGB2ITGAM | |
| SCHEMBL3894013 | 0.90 | MAP3K5 (0.79) | MAP3K5MAPTAPEX1ITGB2ITGAM | |
| SCHEMBL12340045 | 0.89 | ITGB2 (0.72) | MAP3K5MAPTITGB2ITGAMMEN1 | |
| SCHEMBL13056333 | 0.88 | MAP3K5 (0.72) | MAP3K5MAPTAPEX1PTPN22MEN1 | |
| SCHEMBL13081591 | 0.88 | MAP3K5 (0.75) | MAP3K5MAPTAPEX1PTPN22KDM4E | |
| SCHEMBL3905863 | 0.86 | MAP3K5 (1.00) | MAP3K5MAPTAPEX1MEN1KMT2A | |
| SCHEMBL3905865 | 0.86 | MAP3K5 (1.00) | MAP3K5MAPTAPEX1MEN1KMT2A | |
| SCHEMBL16492646 | 0.84 | PTPN22 (0.71) | MAP3K5MAPTAPEX1PTPN22MEN1 | |
| SCHEMBL13762526 | 0.84 | PTPN22 (0.71) | MAP3K5MAPTAPEX1PTPN22MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005041951-A2 | RHODANINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | RIGEL PHARMACEUTICALS, INC. (US) | 2005-05-12 | — | — | WO | disclosed |