Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520707 | 0.88 | TSHR (0.40) | KMT2ACACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL7521187 | 0.81 | CHRM3 (0.37) | KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7527644 | 0.79 | POLB (0.46) | KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7522478 | 0.78 | ATM (0.36) | KMT2A | |
| SCHEMBL7527772 | 0.78 | KMT2A (0.44) | KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7525808 | 0.78 | KMT2A (0.34) | KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7522795 | 0.77 | KMT2A (0.42) | KMT2A | |
| SCHEMBL7529130 | 0.77 | BACE1 (0.34) | KMT2A | |
| SCHEMBL7523899 | 0.77 | IDH1 (0.35) | KMT2ASMN1; SMN2 | |
| SCHEMBL13722775 | 0.77 | GAA (0.42) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058311-A1 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS | SCHERING CORPORATION (US) | 2005-06-30 | — | — | WO | disclosed |