Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.87 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CASP6 | P55212 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3128067 | 0.97 | FLT3 (0.92) | FLT3ALDH1A1HSD17B10TSHRMAPK10 | |
| SCHEMBL8289515 | 0.97 | FLT3 (0.87) | FLT3ALDH1A1HSD17B10TSHRMAPK10 | |
| SCHEMBL8290415 | 0.96 | FLT3 (0.90) | FLT3ALDH1A1HSD17B10TSHRMAPK10 | |
| SCHEMBL3126680 | 0.96 | FLT3 (0.90) | FLT3ALDH1A1HSD17B10TSHRMAPK10 | |
| SCHEMBL5467649 | 0.96 | FLT3 (0.94) | FLT3ALDH1A1HSD17B10TSHRMAPK10 | |
| SCHEMBL3914689 | 0.94 | FLT3 (0.92) | FLT3ALDH1A1HSD17B10TSHRMAPK10 | |
| SCHEMBL8288684 | 0.93 | FLT3 (0.90) | FLT3ALDH1A1HSD17B10TSHRMAPK10 | |
| SCHEMBL3922474 | 0.93 | FLT3 (1.00) | FLT3ALDH1A1HSD17B10TSHRMAPK10 | |
| SCHEMBL5455726 | 0.92 | FLT3 (0.97) | FLT3ALDH1A1HSD17B10TSHRMAPK10 | |
| SCHEMBL8288845 | 0.92 | FLT3 (0.97) | FLT3ALDH1A1HSD17B10TSHRMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |