Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8290488 | 0.99 | HDAC1 (0.59) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL13226936 | 0.90 | HDAC1 (0.74) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL13118189 | 0.89 | HDAC1 (0.73) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL8289364 | 0.85 | HDAC1 (0.82) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL3372282 | 0.83 | HDAC1 (0.55) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL3372287 | 0.83 | HDAC1 (0.55) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL13118185 | 0.79 | HDAC1 (0.83) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL3632825 | 0.79 | HDAC1 (0.47) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL19732376 | 0.76 | HDAC1 (0.52) | HDAC1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL3370990 | 0.76 | HDAC1 (0.55) | HDAC1HDAC8HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005028447-A1 | BENZIMIDAZOLE DERIVATES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2005-03-31 | — | — | WO | disclosed |