Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 15/20 | 0.52 |
| ▸ | TMPRSS6 | Q8IU80 | 4/20 | 0.52 |
| ▸ | TMPRSS11D | O60235 | 9/20 | 0.49 |
| ▸ | F10 | P00742 | 7/20 | 0.48 |
| ▸ | PLG | P00747 | 6/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.48 |
| ▸ | PROC | P04070 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289954 | 0.92 | F10 (0.54) | F2TMPRSS6TMPRSS11DF10PLG | |
| SCHEMBL12156653 | 0.91 | F2 (0.61) | F2TMPRSS6TMPRSS11DF10PLG | |
| SCHEMBL8289952 | 0.90 | F10 (0.52) | F2TMPRSS6TMPRSS11DF10PLG | |
| SCHEMBL8358388 | 0.87 | F2 (0.59) | F2TMPRSS6TMPRSS11DF10PLG | |
| SCHEMBL8346530 | 0.85 | F2 (0.57) | F2TMPRSS6TMPRSS11DF10PLG | |
| SCHEMBL14567283 | 0.84 | F10 (0.58) | F2TMPRSS6TMPRSS11DF10PLG | |
| SCHEMBL8290836 | 0.84 | F10 (0.58) | F2TMPRSS6TMPRSS11DF10PLG | |
| SCHEMBL8290745 | 0.84 | F10 (0.58) | F2TMPRSS6TMPRSS11DF10PLG | |
| SCHEMBL8290806 | 0.84 | F2 (0.47) | F2TMPRSS6TMPRSS11DF10PLG | |
| SCHEMBL8291001 | 0.84 | F10 (0.56) | F2TMPRSS6TMPRSS11DF10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005026198-A1 | BASE-SUBSTITUTED BENZYLAMINE ANALOGS FOR USE AS COAGULATION FACTOR XA INHIBITORS, THE PRODUCTION AND USE THEREOF | CURACYTE CHEMISTRY GMBH (DE) | 2005-03-24 | — | — | WO | disclosed |