Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.32 |
| ▸ | FDPS | P14324 | 3/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | LAP3 | P28838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8291166 | 0.90 | MAPT (0.34) | TSHRSMN1; SMN2MAPTADH1BADH1C | |
| SCHEMBL13009192 | 0.85 | TSHR (0.33) | TSHRSMN1; SMN2 | |
| SCHEMBL9253400 | 0.72 | TSHR (0.48) | TSHRSMN1; SMN2MAPTADH1BADH1C | |
| SCHEMBL11972782 | 0.71 | TSHR (0.46) | TSHRSMN1; SMN2MAPTADH1BADH1C | |
| SCHEMBL11973209 | 0.71 | TSHR (0.46) | TSHRSMN1; SMN2MAPTADH1BADH1C | |
| SCHEMBL1506834 | 0.71 | TSHR (0.46) | TSHRSMN1; SMN2MAPTADH1BADH1C | |
| SCHEMBL1506833 | 0.71 | TSHR (0.46) | TSHRSMN1; SMN2MAPTADH1BADH1C | |
| SCHEMBL11973211 | 0.71 | TSHR (0.46) | TSHRSMN1; SMN2MAPTADH1BADH1C | |
| SCHEMBL11972784 | 0.71 | TSHR (0.46) | TSHRSMN1; SMN2MAPTADH1BADH1C | |
| SCHEMBL2922631 | 0.69 | TSHR (0.82) | TSHRSMN1; SMN2MAPTADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005073214-A2 | NOVEL INHIBITORS OF CHYMASE | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-08-11 | — | — | WO | disclosed |