Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5242760 | 1.00 | KDM4E (0.44) | KDM4ESLC18A2 | |
| SCHEMBL5242769 | 1.00 | KDM4E (0.44) | KDM4ESLC18A2 | |
| SCHEMBL5240401 | 1.00 | KDM4E (0.44) | KDM4ESLC18A2 | |
| SCHEMBL5241524 | 0.79 | KDM4E (0.49) | KDM4E | |
| SCHEMBL5241862 | 0.79 | KDM4E (0.49) | KDM4E | |
| SCHEMBL24322412 | 0.79 | KDM4E (0.49) | KDM4E | |
| SCHEMBL5241870 | 0.79 | KDM4E (0.49) | KDM4E | |
| SCHEMBL5240182 | 0.77 | KDM4E (0.47) | KDM4E | |
| SCHEMBL5242890 | 0.77 | KDM4E (0.47) | KDM4E | |
| SCHEMBL5242998 | 0.77 | KDM4E (0.47) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1455777-B1 | GLYT1 TRANSPORTER INHIBITORS AND USES THEREOF IN TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 2007-11-21 | — | — | EP | disclosed |
| WO-2005049023-A1 | GLYT1 TRANSPORTER INHIBITORS | GLAXO GROUP LIMITED (GB) | 2005-06-02 | — | — | WO | disclosed |
| WO-2003055478-A1 | GLYT1 TRANSPORTER INHIBITORS AND USES THEREOF IN TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-07-10 | — | — | WO | disclosed |