Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 13/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8291250 | 0.94 | ELANE (0.45) | ELANECYP3A4ABCG2 | |
| SCHEMBL12779397 | 0.92 | ELANE (0.46) | ELANECYP3A4ABCG2 | |
| SCHEMBL12053600 | 0.92 | CYP3A4 (0.47) | ELANECYP3A4 | |
| SCHEMBL15178632 | 0.92 | CYP3A4 (0.47) | ELANECYP3A4 | |
| SCHEMBL14013034 | 0.92 | CYP3A4 (0.47) | ELANECYP3A4 | |
| SCHEMBL12772797 | 0.92 | CYP3A4 (0.47) | ELANECYP3A4 | |
| SCHEMBL16470934 | 0.88 | ELANE (0.39) | ELANECYP3A4ABCG2 | |
| SCHEMBL15178633 | 0.87 | CYP3A4 (0.47) | ELANECYP3A4 | |
| SCHEMBL12772801 | 0.87 | CYP3A4 (0.47) | ELANECYP3A4 | |
| SCHEMBL14013035 | 0.87 | CYP3A4 (0.47) | ELANECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1684787-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2014-04-16 | — | — | EP | disclosed |
| WO-2005051410-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-06-09 | — | — | WO | disclosed |