Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13685296 | 1.00 | BACE1 (0.31) | BACE1CTSK | |
| SCHEMBL16349738 | 1.00 | BACE1 (0.31) | BACE1CTSK | |
| SCHEMBL16349815 | 1.00 | BACE1 (0.31) | BACE1CTSK | |
| SCHEMBL13685087 | 0.89 | BACE1 (0.36) | BACE1CTSK | |
| SCHEMBL13684891 | 0.89 | BACE1 (0.36) | BACE1CTSK | |
| SCHEMBL8290582 | 0.89 | BACE1 (0.36) | BACE1CTSK | |
| SCHEMBL8050677 | 0.89 | BACE1 (0.36) | BACE1CTSK | |
| SCHEMBL16349819 | 0.88 | GAA (0.30) | — | |
| SCHEMBL8054288 | 0.88 | GAA (0.30) | — | |
| SCHEMBL13684986 | 0.88 | GAA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030796-A1 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORPORATION (US) | 2005-04-07 | — | — | WO | disclosed |