Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | POLB | P06746 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | RECQL | P46063 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.57 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 4/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | GALK1 | P51570 | 1/20 | 0.46 |
| ▸ | XPA | P23025 | 7/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8290432 | 0.93 | ESR2 (0.72) | ESR2KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL14584108 | 0.91 | ESR2 (0.62) | ESR2KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL8290360 | 0.91 | ESR2 (0.81) | ESR2KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL8291312 | 0.90 | KMT2A (0.72) | ESR2KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL8290540 | 0.87 | SIRT2 (0.51) | ESR2KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL8291240 | 0.86 | ESR2 (0.84) | ESR2KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL19419927 | 0.83 | ESR2 (0.69) | ESR2KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL8290629 | 0.81 | ESR2 (0.57) | ESR2KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL14584255 | 0.81 | SIRT2 (0.52) | ESR2KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL8291187 | 0.81 | ESR2 (0.49) | ESR2KMT2APOLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037752-A1 | Novel alanyl-amino peptidase inhibitors for functionally influencing different cells and treating immunological, inflammatory, neuronal, and other diseases | KEYNEUROTEK PHARMACEUTICALS AG (DE) | 2007-02-15 | — | — | US | disclosed |
| US-20070037752-A1 | Novel alanyl-amino peptidase inhibitors for functionally influencing different cells and treating immunological, inflammatory, neuronal, and other diseases | KEYNEUROTEK PHARMACEUTICALS AG (DE) | 2007-02-15 | — | — | US | disclosed |
| WO-2005037257-A2 | NOVEL ALANYL-AMINO PEPTIDASE INHIBITORS FOR FUNCTIONALLY INFLUENCING DIFFERENT CELLS AND TREATING IMMUNOLOGICAL, INFLAMMATORY, NEURONAL, AND OTHER DISEASES | IMTM GMBH (DE) | 2005-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037752-A1 | Novel alanyl-amino peptidase inhibitors for functionally influencing different cells and treating immunological, inflammatory, neuronal, and other diseases | DNPEP, PREP, ANPEP | ESR2 2544/4885KMT2A 3390/4885POLB 1250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.