Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 17/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3391289 | 0.94 | CMA1 (0.69) | CMA1PRSS1PRSS2CTSGPRSS3 | |
| SCHEMBL3391294 | 0.94 | CMA1 (0.69) | CMA1PRSS1PRSS2CTSGPRSS3 | |
| SCHEMBL999741 | 0.92 | CMA1 (0.61) | CMA1PRSS1PRSS2CTSGPRSS3 | |
| SCHEMBL999745 | 0.92 | CMA1 (0.61) | CMA1PRSS1PRSS2CTSGPRSS3 | |
| SCHEMBL999628 | 0.89 | CMA1 (0.64) | CMA1PRSS1PRSS2CTSGPRSS3 | |
| SCHEMBL999625 | 0.89 | CMA1 (0.64) | CMA1PRSS1PRSS2CTSGPRSS3 | |
| SCHEMBL7908643 | 0.88 | CMA1 (0.71) | CMA1PRSS1PRSS2CTSGPRSS3 | |
| SCHEMBL3774316 | 0.88 | CMA1 (0.68) | CMA1PRSS1PRSS2CTSGPRSS3 | |
| SCHEMBL3774304 | 0.88 | CMA1 (0.68) | CMA1PRSS1PRSS2CTSGPRSS3 | |
| SCHEMBL998173 | 0.88 | CMA1 (0.55) | CMA1PRSS1PRSS2CTSGPRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005073214-A2 | NOVEL INHIBITORS OF CHYMASE | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-08-11 | — | — | WO | disclosed |