Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1065624 | 0.85 | HDAC1 (0.56) | HDAC1HDAC2ABCB1ABCC1MEN1 | |
| SCHEMBL8293246 | 0.81 | HDAC1 (0.51) | HDAC1HDAC2ABCB1MEN1ALDH1A1 | |
| SCHEMBL1067128 | 0.80 | HDAC1 (0.77) | HDAC1HDAC2ABCB1ABCC1MEN1 | |
| SCHEMBL8292282 | 0.80 | HDAC1 (0.62) | HDAC1HDAC2ABCB1MEN1ALDH1A1 | |
| SCHEMBL1066863 | 0.80 | HDAC1 (0.61) | HDAC1HDAC2ABCB1ABCC1MEN1 | |
| SCHEMBL1066464 | 0.79 | HDAC1 (0.58) | HDAC1HDAC2ABCB1MEN1ALDH1A1 | |
| SCHEMBL12963062 | 0.78 | HDAC1 (0.59) | HDAC1HDAC2ABCB1MEN1ALDH1A1 | |
| SCHEMBL1061676 | 0.76 | HDAC1 (0.56) | HDAC1HDAC2ABCB1MEN1ALDH1A1 | |
| SCHEMBL8292257 | 0.76 | HDAC1 (0.54) | HDAC1HDAC2ABCB1MEN1ALDH1A1 | |
| SCHEMBL1067034 | 0.75 | HDAC1 (0.51) | HDAC1HDAC2ABCB1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030704-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2005-04-07 | — | — | WO | disclosed |