Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 0.81 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3367519 | 0.90 | HDAC1 (1.00) | HDAC1HDAC8MEN1LMNAKMT2A | |
| SCHEMBL19185917 | 0.85 | HDAC1 (0.72) | HDAC1HDAC8MEN1LMNAKMT2A | |
| SCHEMBL12560856 | 0.79 | HDAC1 (0.67) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL12561026 | 0.78 | HDAC1 (0.65) | HDAC1HDAC8LMNAHDAC3HDAC4 | |
| SCHEMBL23192217 | 0.78 | HDAC1 (0.65) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL3369926 | 0.77 | HDAC1 (0.78) | HDAC1HDAC8MEN1LMNAKMT2A | |
| SCHEMBL19185706 | 0.76 | HDAC1 (0.56) | HDAC1HDAC8MEN1LMNAKMT2A | |
| SCHEMBL10298792 | 0.75 | MEN1 (0.49) | HDAC1HDAC8MEN1LMNAKMT2A | |
| SCHEMBL19185684 | 0.73 | HDAC1 (0.55) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL13118138 | 0.73 | HDAC1 (0.64) | HDAC1HDAC8HDAC3HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005028447-A1 | BENZIMIDAZOLE DERIVATES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2005-03-31 | — | — | WO | disclosed |