Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3870480 | 0.78 | POLB (0.34) | POLB | |
| SCHEMBL3870481 | 0.78 | POLB (0.34) | POLB | |
| SCHEMBL8362651 | 0.78 | POLB (0.34) | POLB | |
| Hydrochloric Acid SCHEMBL3870064 | 0.77 | POLB (0.33) | POLB | |
| Hydrochloric Acid SCHEMBL3870061 | 0.77 | POLB (0.33) | POLB | |
| SCHEMBL13827635 | 0.72 | POLB (0.40) | POLB | |
| SCHEMBL469197 | 0.72 | POLB (0.40) | POLB | |
| Hydrochloric Acid SCHEMBL20559927 | 0.71 | IDH1 (0.36) | POLB | |
| Hydrochloric Acid SCHEMBL20559925 | 0.71 | IDH1 (0.36) | POLB | |
| SCHEMBL5565029 | 0.69 | IDH1 (0.36) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040142-A1 | NOVEL KETO-OXADIAZOLE DERIVATIVES AS CATHEPSIN INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2005-05-06 | — | — | WO | disclosed |