Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 19/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8293185 | 0.89 | TDP1 (0.55) | TDP1DPP4DPP7DPP8DPP9 | |
| SCHEMBL8294408 | 0.86 | TDP1 (0.68) | TDP1DPP4DPP7DPP8DPP9 | |
| SCHEMBL8294713 | 0.85 | TDP1 (0.51) | TDP1DPP4DPP7DPP8DPP9 | |
| SCHEMBL8295415 | 0.85 | TDP1 (0.51) | TDP1DPP4DPP7DPP8DPP9 | |
| SCHEMBL8293182 | 0.84 | DPP4 (0.55) | TDP1DPP4DPP7DPP8DPP9 | |
| SCHEMBL5661437 | 0.84 | DPP4 (0.53) | TDP1DPP4DPP7DPP8DPP9 | |
| SCHEMBL21067942 | 0.84 | DPP4 (0.53) | TDP1DPP4DPP7DPP8DPP9 | |
| SCHEMBL21067940 | 0.84 | DPP4 (0.53) | TDP1DPP4DPP7DPP8DPP9 | |
| SCHEMBL8293188 | 0.84 | TDP1 (0.55) | TDP1DPP4DPP7DPP8DPP9 | |
| SCHEMBL8293194 | 0.84 | TDP1 (0.55) | TDP1DPP4DPP7DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056013-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2005-06-23 | — | — | WO | disclosed |