Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8291718 | 0.89 | MEN1 (0.58) | TSHRKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL9225683 | 0.87 | KDM4E (0.54) | TSHRKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL8299745 | 0.87 | HPGD (0.57) | TSHRKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL8297761 | 0.87 | HSD17B10 (0.69) | TSHRKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL8293093 | 0.85 | HPGD (0.59) | TSHRKDM4EMEN1KMT2AHPGD | |
| SCHEMBL8301382 | 0.83 | MCHR1 (0.63) | TSHRKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL8212431 | 0.82 | TDP1 (0.54) | TSHRKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL8300413 | 0.82 | MEN1 (0.58) | TSHRKDM4EMEN1KMT2AHPGD | |
| SCHEMBL8301652 | 0.82 | KMT2A (0.61) | TSHRKDM4EMEN1KMT2AHPGD | |
| SCHEMBL8300986 | 0.81 | HPGD (0.71) | TSHRKDM4EMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| CN-1118595-A | Anthranilic acid derivative | EISAI CO LTD (JP) | 1996-03-13 | — | — | CN | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |