Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL161702 | 0.79 | KMT2A (0.45) | KMT2AMEN1GAAHSD17B10MLYCD | |
| SCHEMBL14022267 | 0.78 | PRKCI (0.48) | KMT2AMEN1GAAHSD17B10MLYCD | |
| SCHEMBL27949692 | 0.72 | EGLN2 (0.63) | KMT2AMEN1GAAHSD17B10MLYCD | |
| SCHEMBL13697276 | 0.70 | PDE3B (0.36) | KMT2AALDH1A1POLB | |
| SCHEMBL13593756 | 0.69 | KDM4E (0.59) | KMT2AMEN1HPGDRAB9ANPSR1 | |
| SCHEMBL24598452 | 0.69 | CTSA (0.51) | KMT2AGAAHSD17B10HPGDNPSR1 | |
| SCHEMBL5158053 | 0.68 | KDM4E (0.42) | KMT2ANPSR1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL30542671 | 0.68 | KMT2A (0.44) | KMT2AMEN1GAAHSD17B10MLYCD | |
| SCHEMBL28660959 | 0.68 | KMT2A (0.44) | KMT2AMEN1GAAHSD17B10MLYCD | |
| SCHEMBL13726817 | 0.68 | KMT2A (0.48) | KMT2AMEN1GAAHSD17B10MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005021584-A2 | NOVEL PEPTIDOMIMETIC NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2005-03-10 | — | — | WO | disclosed |