Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | PAK1 | Q13153 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8293592 | 1.00 | SLC29A1 (0.50) | SLC29A1GRIN2BKCNH2LMNAHPGDS | |
| SCHEMBL8291847 | 1.00 | SLC29A1 (0.50) | SLC29A1GRIN2BKCNH2LMNAHPGDS | |
| SCHEMBL8293768 | 1.00 | SLC29A1 (0.50) | SLC29A1GRIN2BKCNH2LMNAHPGDS | |
| SCHEMBL8292785 | 1.00 | SLC29A1 (0.50) | SLC29A1GRIN2BKCNH2LMNAHPGDS | |
| Hydrochloric Acid SCHEMBL5007175 | 0.99 | SLC29A1 (0.49) | SLC29A1GRIN2BKCNH2LMNAHPGDS | |
| SCHEMBL14010524 | 0.88 | SLC29A1 (0.54) | SLC29A1GRIN2BKCNH2LMNAHPGDS | |
| SCHEMBL8291850 | 0.88 | SLC29A1 (0.54) | SLC29A1GRIN2BKCNH2LMNAHPGDS | |
| SCHEMBL8291841 | 0.86 | SLC29A1 (0.54) | SLC29A1GRIN2BKCNH2LMNAHPGDS | |
| SCHEMBL14010240 | 0.86 | SLC29A1 (0.54) | SLC29A1GRIN2BKCNH2LMNAHPGDS | |
| SCHEMBL14010256 | 0.86 | SLC29A1 (0.54) | SLC29A1GRIN2BKCNH2LMNAHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019222-A1 | 4-CYCLOALKYLAMINOPYRAZOLO PYRIMIDINE NMDA/NR2B ANTAGONISTS | MERCK & CO., INC. (US) | 2005-03-03 | — | — | WO | disclosed |