Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.33 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968939 | 1.00 | ADRB3 (0.41) | ADRB3ADRA2BADRA2CCYP3A4BCL2 | |
| SCHEMBL3970892 | 1.00 | ADRB3 (0.41) | ADRB3ADRA2BADRA2CCYP3A4BCL2 | |
| SCHEMBL3969664 | 1.00 | ADRB3 (0.41) | ADRB3ADRA2BADRA2CCYP3A4BCL2 | |
| SCHEMBL3787948 | 0.96 | ADRB3 (0.41) | ADRB3ADRA2BADRA2CCYP3A4RAMP1 | |
| SCHEMBL3787952 | 0.96 | ADRB3 (0.41) | ADRB3ADRA2BADRA2CCYP3A4RAMP1 | |
| SCHEMBL3787944 | 0.96 | ADRB3 (0.41) | ADRB3ADRA2BADRA2CCYP3A4RAMP1 | |
| SCHEMBL3965120 | 0.94 | ADRB3 (0.45) | ADRB3ADRA2BADRA2CCYP3A4BCL2 | |
| SCHEMBL3965128 | 0.94 | ADRB3 (0.45) | ADRB3ADRA2BADRA2CCYP3A4BCL2 | |
| SCHEMBL3965124 | 0.94 | ADRB3 (0.45) | ADRB3ADRA2BADRA2CCYP3A4BCL2 | |
| SCHEMBL3965585 | 0.92 | ADRB3 (0.46) | ADRB3ADRA2BADRA2CCYP3A4BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037214-A2 | MACROCYCLIC CARBOXYLIC ACIDS AND ACYLSULFONAMIDES AS INHIBITORS OF HCV REPLICATION | INTERMUNE, INC. (US) | 2005-04-28 | — | — | WO | disclosed |