SCHEMBL829392

SCHEMBL829392

[CH2]CCCC[CH]C(=O)C=C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ABCC4 O15439 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7791214 0.82
SCHEMBL27825567 0.79 TSHR (0.46) MAPT
SCHEMBL6422980 0.76
SCHEMBL4418767 0.75
SCHEMBL19372057 0.74 TSHR (0.39) MAPT
SCHEMBL4419963 0.73 MAPT (0.38) ABCC4MAPT
SCHEMBL10610970 0.73 MAPT (0.38) ABCC4MAPT
SCHEMBL10609909 0.73 MAPT (0.38) ABCC4MAPT
SCHEMBL10611257 0.73 MAPT (0.38) ABCC4MAPT
SCHEMBL10611067 0.73 MAPT (0.38) ABCC4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0588875-B1 MICROSPHERES USEFUL FOR THERAPEUTIC VASCULAR OCCLUSIONS AND INJECTABLE SOLUTIONS CONTAINING THE SAME BIOSEPRA SA (FR) 1997-04-09 EP claimed
EP-0588875-A4 1994-08-03 EP claimed
EP-0588875-A1 MICROSPHERES USEFUL FOR THERAPEUTIC VASCULAR OCCLUSIONS AND INJECTABLE SOLUTIONS CONTAINING THE SAME. SEPRACOR INC (US) 1994-03-30 EP claimed
WO-1992021327-A1 MICROSPHERES USEFUL FOR THERAPEUTIC VASCULAR OCCLUSIONS AND INJECTABLE SOLUTIONS CONTAINING THE SAME SEPRACOR, INC. (US) 1992-12-10 WO claimed
EP-0099058-B1 PROCESS FOR PRODUCING LOW-SHRINK POLYAMIDE MOULDED ARTICLES BASF Aktiengesellschaft (DE) 1986-04-23 EP claimed
US-11845823-B2 Radiopaque monomers, polymers, microspheres, and methods related thereto BIOSPHERE MEDICAL, INC. (US) 2023-12-19 US disclosed
EP-4245782-A1 RADIOPAQUE MONOMERS, POLYMERS, MICROSPHERES, AND METHODS RELATED THERETO BIOSPHERE MEDICAL, INC. (US) 2023-09-20 EP disclosed
EP-3660061-B1 RADIOPAQUE MONOMERS, POLYMERS, MICROSPHERES, AND METHODS RELATED THERETO BIOSPHERE MEDICAL INC (US) 2023-06-21 EP disclosed
US-20220016270-A1 RADIOPAQUE MONOMERS, POLYMERS, MICROSPHERES, AND METHODS RELATED THERETO WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2022-01-20 US disclosed
US-11116855-B2 Radiopaque monomers, polymers, microspheres, and methods related thereto BIOSPHERE MEDICAL, INC. (US) 2021-09-14 US disclosed
EP-3245236-B1 RADIOPAQUE MONOMERS, POLYMERS, MICROSPHERES, AND METHODS RELATED THERETO BIOSPHERE MEDICAL INC (US) 2020-09-23 EP disclosed
EP-3660061-A1 RADIOPAQUE MONOMERS, POLYMERS, MICROSPHERES, AND METHODS RELATED THERETO BIOSPHERE MEDICAL, INC. (US) 2020-06-03 EP disclosed
EP-1059943-A1 IMPLANTABLE PARTICLES FOR TISSUE BULKING AND THE TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE, URINARY INCONTINENCE, AND SKIN WRINKLES Biosepra Medical Inc. (US) 2000-12-20 EP disclosed
WO-1999044643-A1 IMPLANTABLE PARTICLES FOR TISSUE BULKING AND THE TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE, URINARY INCONTINENCE, AND SKIN WRINKLES BIOSEPRA MEDICAL INC. (US) 1999-09-10 WO disclosed
US-5648100-A Microspheres useful for therapeutic vascular occlusions and injectable solutions containing the same ASSISTANCE PUBLIQUE HOPITAUX DE PARIS (FR) 1997-07-15 US disclosed
US-5635215-A Microspheres useful for therapeutic vascular occlusions and injectable solutions containing the same BIOSEPRA S.A. (FR) 1997-06-03 US disclosed
EP-0588875-B1 MICROSPHERES USEFUL FOR THERAPEUTIC VASCULAR OCCLUSIONS AND INJECTABLE SOLUTIONS CONTAINING THE SAME BIOSEPRA SA (FR) 1997-04-09 EP disclosed
EP-0588875-A4 1994-08-03 EP disclosed
EP-0588875-A1 MICROSPHERES USEFUL FOR THERAPEUTIC VASCULAR OCCLUSIONS AND INJECTABLE SOLUTIONS CONTAINING THE SAME. SEPRACOR INC (US) 1994-03-30 EP disclosed
WO-1992021327-A1 MICROSPHERES USEFUL FOR THERAPEUTIC VASCULAR OCCLUSIONS AND INJECTABLE SOLUTIONS CONTAINING THE SAME SEPRACOR, INC. (US) 1992-12-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220016270-A1 RADIOPAQUE MONOMERS, POLYMERS, MICROSPHERES, AND METHODS RELATED THERETO CD68, MVD, RAD54L ABCC4 4534/4885MAPT 1802/4885
US-11116855-B2 Radiopaque monomers, polymers, microspheres, and methods related thereto CD68, MVD, RAD54L ABCC4 4534/4885MAPT 1802/4885
US-11845823-B2 Radiopaque monomers, polymers, microspheres, and methods related thereto CD68, MVD, RAD54L ABCC4 4534/4885MAPT 1802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.