Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24444285 | 0.78 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2ATMHPGDKDM4E | |
| SCHEMBL1952673 | 0.76 | SMN1; SMN2 (0.60) | ALDH1A1SMN1; SMN2ATMMEN1LMNA | |
| SCHEMBL18972040 | 0.76 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2ATMHPGDCASP6 | |
| SCHEMBL22570787 | 0.76 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2ATMDPP4KDM4E | |
| SCHEMBL18907365 | 0.76 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2ATMHPGDCASP6 | |
| SCHEMBL18909886 | 0.76 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2ATMHPGDCASP6 | |
| SCHEMBL8275256 | 0.76 | ATM (0.48) | ALDH1A1SMN1; SMN2ATMKDM4EEPHX1 | |
| SCHEMBL17476039 | 0.76 | KMT2A (0.56) | ALDH1A1SMN1; SMN2ATMMEN1LMNA | |
| SCHEMBL13645855 | 0.75 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2ATMMEN1LMNA | |
| SCHEMBL22314758 | 0.74 | DPP4 (0.46) | ALDH1A1SMN1; SMN2ATMLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005025554-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | JAPAN TOBACCO INC. (JP) | 2005-03-24 | — | — | WO | disclosed |