Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2A | Q92830 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2688933 | 0.87 | — | — | |
| SCHEMBL8294533 | 0.81 | KAT2A (0.32) | KAT2AMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL2692978 | 0.79 | KAT2A (0.38) | KAT2AMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL2692000 | 0.74 | — | — | |
| SCHEMBL22721612 | 0.73 | — | — | |
| SCHEMBL2692031 | 0.70 | ELANE (0.41) | KAT2AMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL12534307 | 0.68 | KAT2A (0.32) | KAT2AMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL2690735 | 0.68 | — | — | |
| SCHEMBL23048857 | 0.67 | MEN1 (0.36) | KAT2AMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL12660142 | 0.67 | KAT2A (0.35) | KAT2AMEN1KMT2ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2327701-A1 | Heteroarylaminosulfonylphenyl derivatives for use as sodium or calcium channel blockers in the treatment of pain | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-06-01 | — | — | EP | disclosed |
| WO-2005013914-A2 | HETEROARYLAMINOSULFONYLPHENYL DERIVATIVES FOR USE AS SODIUM OR CALCIUM CHANNEL BLOCKERS IN THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2005-02-17 | — | — | WO | disclosed |