Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL331899 | 0.94 | PDE5A (0.58) | PDE5AKCNH2 | |
| SCHEMBL331941 | 0.90 | PDE5A (0.68) | PDE5AKCNH2 | |
| SCHEMBL332265 | 0.89 | PDE5A (0.59) | PDE5AKCNH2 | |
| SCHEMBL331421 | 0.86 | PDE5A (0.60) | PDE5AKCNH2 | |
| SCHEMBL331742 | 0.86 | PDE5A (0.69) | PDE5AKCNH2 | |
| SCHEMBL331641 | 0.85 | PDE5A (0.62) | PDE5AKCNH2 | |
| SCHEMBL13757005 | 0.84 | PDE5A (0.54) | PDE5AKCNH2 | |
| SCHEMBL331541 | 0.84 | PDE5A (0.72) | PDE5AKCNH2 | |
| SCHEMBL331626 | 0.84 | PDE5A (0.57) | PDE5AKCNH2 | |
| SCHEMBL2870991 | 0.82 | PDE5A (0.70) | PDE5AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049616-A1 | 5,7-DIAMINOPYRAZOLO [4,3-d] PYRIMIDINES WITH PDE-5 INHIBITING ACTIVITY | PFIZER LIMITED (GB) | 2005-06-02 | — | — | WO | disclosed |