Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14003262 | 1.00 | DPP4 (0.40) | DPP4DPP8DPP7AAK1DPP9 | |
| SCHEMBL6358505 | 0.89 | DPP4 (0.41) | DPP4DPP8DPP7AAK1DPP9 | |
| SCHEMBL6358510 | 0.89 | DPP4 (0.41) | DPP4DPP8DPP7AAK1DPP9 | |
| SCHEMBL6358508 | 0.89 | DPP4 (0.41) | DPP4DPP8DPP7AAK1DPP9 | |
| SCHEMBL6809878 | 0.89 | DPP4 (0.52) | DPP4DPP8DPP7AAK1DPP9 | |
| SCHEMBL6809881 | 0.89 | DPP4 (0.52) | DPP4DPP8DPP7AAK1DPP9 | |
| SCHEMBL8276054 | 0.86 | DPP4 (0.44) | DPP4DPP8DPP7DPP9KCNH2 | |
| SCHEMBL13412180 | 0.86 | DPP4 (0.44) | DPP4DPP8DPP7DPP9KCNH2 | |
| SCHEMBL14003263 | 0.86 | DPP4 (0.39) | DPP4DPP8DPP7AAK1DPP9 | |
| SCHEMBL14027242 | 0.86 | DPP4 (0.39) | DPP4DPP8DPP7AAK1DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456204-B2 | Cyclohexylglycine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes | MERCK & CO., INC. (US) | 2008-11-25 | — | — | US | disclosed |
| WO-2004112701-A2 | CYCLOHEXYLGLYCINE DERIVATIVES AS DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK & CO., INC. (US) | 2004-12-29 | — | — | WO | disclosed |