Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 11/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27636683 | 0.96 | EPHX1 (0.52) | EPHX1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8294199 | 0.96 | EPHX1 (0.52) | EPHX1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL22679468 | 0.96 | EPHX1 (0.52) | EPHX1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8294194 | 0.94 | EPHX1 (0.50) | EPHX1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL19820046 | 0.94 | EPHX1 (0.48) | EPHX1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL1174761 | 0.79 | DPP4 (0.46) | EPHX1DPP4GLSDPP7 | |
| SCHEMBL1174765 | 0.79 | DPP4 (0.46) | EPHX1DPP4GLSDPP7 | |
| SCHEMBL14097634 | 0.79 | DPP4 (0.46) | EPHX1DPP4GLSDPP7 | |
| SCHEMBL12154903 | 0.78 | DPP4 (0.44) | EPHX1DPP4GLSDPP7 | |
| Hydrochloric Acid SCHEMBL1300426 | 0.78 | DPP4 (0.44) | EPHX1DPP4GLSDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005025554-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | JAPAN TOBACCO INC. (JP) | 2005-03-24 | — | — | WO | disclosed |