Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 6/20 | 0.63 |
| ▸ | GRIK2 | Q13002 | 6/20 | 0.63 |
| ▸ | GRIK5 | Q16478 | 5/20 | 0.63 |
| ▸ | GRIK3 | Q13003 | 4/20 | 0.63 |
| ▸ | GRIK4 | Q16099 | 4/20 | 0.63 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.60 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.60 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.60 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8290910 | 0.89 | GRIK1 (0.59) | GRIK1GRIK2GRIK5GRIK3GRIK4 | |
| Hydrochloric Acid SCHEMBL8129889 | 0.83 | SLC22A6 (0.72) | GRIK1GRIK2GRIK5GRIK3GRIK4 | |
| SCHEMBL8609604 | 0.82 | GRIK1 (0.78) | GRIK1GRIK2GRIK5GRIK3GRIK4 | |
| Sulfuric Acid SCHEMBL8200151 | 0.80 | SLC22A6 (0.70) | GRIK1GRIK2GRIK5GRIK3GRIK4 | |
| SCHEMBL8292029 | 0.79 | GRIK1 (0.50) | GRIK1GRIK2GRIK5GRIK3GRIK4 | |
| SCHEMBL8609255 | 0.78 | GRIK1 (0.69) | GRIK1GRIK2GRIK5GRIK3GRIK4 | |
| SCHEMBL8613051 | 0.77 | GRIK1 (0.71) | GRIK1GRIK2GRIK5GRIK3GRIK4 | |
| SCHEMBL8291676 | 0.77 | GRIA1 (0.78) | GRIK1GRIK2GRIK5GRIK3GRIK4 | |
| Hydrochloric Acid SCHEMBL8129882 | 0.76 | SLC22A6 (0.68) | GRIK1GRIK2GRIK5GRIK3GRIK4 | |
| Sulfuric Acid SCHEMBL8192619 | 0.75 | SLC22A6 (0.68) | GRIK1GRIK2GRIK5GRIK3GRIK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676397-B1 | Oxopyridinylquinoxaline derivatives | SHIONOGI & CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5677305-A | NERVOUS SYSTEM DISORDERS | SHIONOGI & CO., LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| EP-0676397-A1 | Oxopyridinylquinoxaline derivatives | SHIONOGI & CO., LTD. (JP) | 1995-10-11 | — | — | EP | disclosed |