⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10537874 | 0.82 | — | — | |
| SCHEMBL5984673 | 0.82 | — | — | |
| SCHEMBL56255 | 0.82 | — | — | |
| SCHEMBL9021463 | 0.76 | — | — | |
| SCHEMBL8813173 | 0.76 | — | — | |
| SCHEMBL4448690 | 0.76 | — | — | |
| SCHEMBL9021494 | 0.76 | — | — | |
| SCHEMBL270391 | 0.76 | — | — | |
| SCHEMBL5984895 | 0.76 | — | — | |
| SCHEMBL6551754 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357268-A1 | PREPARATION AND APPLICATION OF TRICYCLIC PYRIMIDINONE COMPOUND AND ITS COMPOSITION | NEUSCO BIOTECH LIMITED (CN) | 2023-11-09 | — | — | US | claimed |
| US-20230271980-A1 | PREPARATION AND APPLICATION OF TRICYCLIC PYRIMIDINONE COMPOUND AND ITS COMPOSITION | NEUSCO BIOTECH LIMITED (CN) | 2023-08-31 | — | — | US | claimed |
| US-20230212168-A1 | ENDOCYCLIC PYRIMIDINONE COMPOUNDS, AND PREPARATION METHODS, COMPOSITIONS AND USE THEREOF | NEUSCO BIOTECH LIMITED (CN) | 2023-07-06 | — | — | US | claimed |
| EP-4180436-A1 | TRICYCLIC PYRIMIDINONE COMPOUND, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF | Neusco Biotech Limited (CN) | 2023-05-17 | — | — | EP | claimed |
| EP-4174070-A1 | TRICYCLIC PYRIMIDINONE COMPOUND, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF | Neusco Biotech Limited (CN) | 2023-05-03 | — | — | EP | claimed |
| EP-4151638-A1 | BRIDGED CYCLIC PYRIMIDINONE COMPOUND, PREPARATION METHOD THEREFOR, COMPOSITION CONTAINING SAME AND USE THEREOF | Neusco Biotech Limited (CN) | 2023-03-22 | — | — | EP | claimed |
| CN-113912622-A | Tricyclic pyrimidone compounds, preparation method, composition and application thereof | 上海纽思克生物科技有限公司 | 2022-01-11 | — | — | CN | claimed |
| WO-2022001881-A1 | TRICYCLIC PYRIMIDINONE COMPOUND, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF | 上海纽思克生物科技有限公司 | 2022-01-06 | — | — | WO | claimed |
| CN-113861220-A | Tricyclic pyrimidone compounds, preparation method, composition and application thereof | 上海纽思克生物科技有限公司 | 2021-12-31 | — | — | CN | claimed |
| CN-113666930-A | Bridged pyrimidone compounds, preparation method, composition and application thereof | 上海纽思克生物科技有限公司 | 2021-11-19 | — | — | CN | claimed |
| WO-2021063145-A1 | TETRACYCLIC PYRIMIDINONE COMPOUND, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF | 上海纽思克生物科技有限公司 | 2021-04-08 | — | — | WO | claimed |
| CN-112574221-A | Tetracyclic pyrimidinone compounds, preparation method, composition and application thereof | 上海纽思克生物科技有限公司 | 2021-03-30 | — | — | CN | claimed |
| US-8299245-B2 | Method for producing pyrimidine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-30 | — | — | US | claimed |
| US-20090111984-A1 | Novel Method For Producing Pyrimidine Compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-04-30 | — | — | US | claimed |
| EP-2011795-A1 | NOVEL PROCESS FOR PRODUCTION OF PYRIMIDINE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2009-01-07 | — | — | EP | claimed |
| EP-3994117-B1 | HYDROGENATION OF ESTERS TO ALCOHOLS IN THE PRESENCE OF A RU-PNN COMPLEX | BASF SE (DE) | 2024-07-03 | — | — | EP | disclosed |
| US-20240191093-A1 | INKJET INK, INKJET RECORDING METHOD, INK SET, INK MEDIUM SET, AND PRINT MEDIUM | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2024-06-13 | — | — | US | disclosed |
| US-4112105-A | Anti-inflammatory 3-(substituted-amino)-2,1-benzisothiazoles | STERLING DRUG INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |
| US-3956397-A | Process for extracting cycloaliphatic hydroperoxides | RHONE-POULENC INDUSTRIES (FR) | 1976-05-11 | — | — | US | disclosed |