Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 2/20 | 0.49 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1419385 | 1.00 | KCNA5 (0.49) | KCNA5GBA1KMT2ASMN1; SMN2F2 | |
| SCHEMBL21459309 | 1.00 | KCNA5 (0.49) | KCNA5GBA1KMT2ASMN1; SMN2F2 | |
| Hydrochloric Acid SCHEMBL21459882 | 0.98 | KCNA5 (0.48) | KCNA5GBA1KMT2ASMN1; SMN2F2 | |
| Hydrochloric Acid SCHEMBL21459880 | 0.98 | KCNA5 (0.48) | KCNA5GBA1KMT2ASMN1; SMN2F2 | |
| SCHEMBL22699240 | 0.85 | F10 (0.42) | GBA1KMT2AF2F10ALDH1A1 | |
| SCHEMBL20545317 | 0.85 | F10 (0.42) | GBA1KMT2AF2F10ALDH1A1 | |
| SCHEMBL21476155 | 0.85 | F10 (0.42) | GBA1KMT2AF2F10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL19067189 | 0.84 | IDO1 (0.43) | GBA1F2F10ALDH1A1CTSA | |
| SCHEMBL24036698 | 0.84 | KCNA5 (0.37) | KCNA5KMT2AF2F10ALDH1A1 | |
| SCHEMBL25623852 | 0.84 | KCNA5 (0.37) | KCNA5KMT2AF2F10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |