Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3308384 | 0.98 | CTDSP1 (0.41) | CTDSP1CDC25ATHRBLMNATSHR | |
| SCHEMBL1962073 | 0.93 | CDC25A (0.37) | CTDSP1CDC25ATHRBLMNATSHR | |
| Hydrochloric Acid SCHEMBL6567666 | 0.91 | CDC25A (0.36) | CTDSP1CDC25ATHRBLMNATSHR | |
| SCHEMBL9936179 | 0.91 | CDC25A (0.36) | CTDSP1CDC25ATHRBLMNATSHR | |
| Water SCHEMBL11593967 | 0.91 | CDC25A (0.36) | CTDSP1CDC25ATHRBLMNATSHR | |
| SCHEMBL9935048 | 0.91 | CDC25A (0.36) | CTDSP1CDC25ATHRBLMNATSHR | |
| Iodide SCHEMBL10751393 | 0.91 | CTDSP1 (0.39) | CTDSP1CDC25ATHRBLMNATSHR | |
| SCHEMBL9935636 | 0.91 | CTDSP1 (0.42) | CTDSP1CDC25ATHRB | |
| SCHEMBL29975144 | 0.89 | CDC25A (0.40) | CTDSP1CDC25ATHRBTSHR | |
| SCHEMBL12638482 | 0.89 | CDC25A (0.38) | CTDSP1CDC25ATHRBLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2089414-B1 | USE OF IONIC LIQUIDS FOR MEMBRANE PROTEIN EXTRACTION | MERCK PATENT GMBH (DE) | 2013-03-06 | — | — | EP | claimed |
| US-8143381-B2 | Use of ionic liquids for membrane protein extraction | MERCK PATENT GMBH (DE) | 2012-03-27 | — | — | US | claimed |
| US-20100029917-A1 | USE OF IONIC LIQUIDS FOR MEMBRANE PROTEIN EXTRACTION | MERCK PATENT GMBH (DE) | 2010-02-04 | — | — | US | claimed |
| EP-2089414-A1 | USE OF IONIC LIQUIDS FOR MEMBRANE PROTEIN EXTRACTION | Merck Patent GmbH (DE) | 2009-08-19 | — | — | EP | claimed |
| WO-2008058604-A1 | USE OF IONIC LIQUIDS FOR MEMBRANE PROTEIN EXTRACTION | MERCK PATENT GMBH (DE) | 2008-05-22 | — | — | WO | claimed |
| EP-2089414-B1 | USE OF IONIC LIQUIDS FOR MEMBRANE PROTEIN EXTRACTION | MERCK PATENT GMBH (DE) | 2013-03-06 | — | — | EP | disclosed |
| US-8143381-B2 | Use of ionic liquids for membrane protein extraction | MERCK PATENT GMBH (DE) | 2012-03-27 | — | — | US | disclosed |
| US-20100029917-A1 | USE OF IONIC LIQUIDS FOR MEMBRANE PROTEIN EXTRACTION | MERCK PATENT GMBH (DE) | 2010-02-04 | — | — | US | disclosed |
| EP-2089414-A1 | USE OF IONIC LIQUIDS FOR MEMBRANE PROTEIN EXTRACTION | Merck Patent GmbH (DE) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008058604-A1 | USE OF IONIC LIQUIDS FOR MEMBRANE PROTEIN EXTRACTION | MERCK PATENT GMBH (DE) | 2008-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029917-A1 | USE OF IONIC LIQUIDS FOR MEMBRANE PROTEIN EXTRACTION | APMAP, VAMP8, VAMP7 | CTDSP1 4581/4885CDC25A 4145/4885THRB 3664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.