Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 4/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | TPMT | P51580 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10131587 | 0.85 | TSHR (0.52) | MEN1KMT2AGAATSHRCYP2C9 | |
| SCHEMBL16795704 | 0.85 | CYP2C9 (0.55) | MEN1KMT2AGAATSHRCYP2C9 | |
| SCHEMBL8152340 | 0.83 | CYP2C9 (0.53) | MEN1KMT2AGAATSHRCYP2C9 | |
| SCHEMBL14611953 | 0.83 | MAOB (0.58) | MEN1KMT2AGAATSHRCYP2C9 | |
| SCHEMBL14375953 | 0.79 | PDE4A (0.79) | MEN1KMT2AGAATSHRCYP2C9 | |
| SCHEMBL7943556 | 0.78 | CA12 (0.64) | MEN1KMT2AGAATSHRCYP2C9 | |
| SCHEMBL18848298 | 0.78 | CYP2C9 (0.61) | MEN1KMT2AGAATSHRCYP2C9 | |
| SCHEMBL8296526 | 0.78 | CYP2C9 (0.61) | MEN1KMT2AGAATSHRCYP2C9 | |
| SCHEMBL14395698 | 0.78 | CA12 (0.59) | MEN1KMT2AGAATSHRCYP2C9 | |
| SCHEMBL9781940 | 0.77 | MEN1 (0.59) | MEN1KMT2AGAATSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997836-A | Inhibitor of platelet activating factor | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-03-05 | — | — | US | disclosed |
| EP-0368670-A1 | Trisubstituted piperazine compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-05-16 | — | — | EP | disclosed |