Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 4/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471463 | 0.88 | FFAR1 (0.57) | FFAR1FFAR4MAPTNPSR1PGR | |
| SCHEMBL1472149 | 0.80 | FFAR1 (0.61) | FFAR1FFAR4MAPTNPSR1PGR | |
| SCHEMBL1471643 | 0.77 | BCL2L1 (0.52) | FFAR1FFAR4MAPTNPSR1PGR | |
| SCHEMBL15480553 | 0.73 | BCL2L1 (0.60) | MAPTNPSR1PGRPOLBMEN1 | |
| SCHEMBL1472283 | 0.72 | BCL2L1 (0.53) | FFAR4MAPTNPSR1PGRPOLB | |
| SCHEMBL1472284 | 0.71 | MAPT (0.56) | MAPTPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL31596007 | 0.70 | FFAR1 (0.76) | FFAR1FFAR4MAPTPGRCACNA1H | |
| Hydrochloric Acid SCHEMBL5797951 | 0.70 | MAPK1 (0.71) | FFAR1FFAR4MAPTPGRMEN1 | |
| SCHEMBL1471525 | 0.69 | MEN1 (0.62) | FFAR1FFAR4MAPTCACNA1HCACNA1B | |
| SCHEMBL1472212 | 0.69 | FFAR1 (0.64) | FFAR1FFAR4MAPTNPSR1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007621-A2 | UBIQUITIN LIGASE INHIBITORS | RIGEL PHARMACEUTICALS, INC. (US) | 2005-01-27 | — | — | WO | disclosed |