Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300712 | 1.00 | TP53 (0.63) | TP53LMNAKMT2A | |
| SCHEMBL6616848 | 0.88 | KMT2A (0.59) | TP53LMNAKMT2A | |
| SCHEMBL6616845 | 0.88 | KMT2A (0.59) | TP53LMNAKMT2A | |
| SCHEMBL6604542 | 0.86 | — | — | |
| SCHEMBL6604547 | 0.86 | — | — | |
| SCHEMBL6216766 | 0.85 | — | — | |
| SCHEMBL6600609 | 0.85 | — | — | |
| SCHEMBL6600612 | 0.85 | — | — | |
| SCHEMBL6601034 | 0.84 | — | — | |
| SCHEMBL6601044 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934934-A2 | Methods of preparing substituted 3-phenyl- and 3-pyridyl-4(3H)-quinazolinones and atropisomers thereof | Pfizer Products Inc. (US) | 1999-08-11 | — | — | EP | disclosed |