Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14488681 | 1.00 | F10 (0.53) | F10KDM4D | |
| SCHEMBL14488778 | 0.91 | F10 (0.44) | F10KDM4D | |
| SCHEMBL14488810 | 0.89 | F10 (0.42) | F10KDM4D | |
| SCHEMBL14489105 | 0.89 | F10 (0.42) | F10KDM4D | |
| SCHEMBL14488708 | 0.89 | F10 (0.42) | F10KDM4D | |
| SCHEMBL14488773 | 0.88 | F10 (0.43) | F10KDM4D | |
| SCHEMBL8298740 | 0.87 | F10 (0.40) | F10KDM4D | |
| SCHEMBL14488738 | 0.87 | F10 (0.40) | F10KDM4D | |
| SCHEMBL5936046 | 0.86 | F10 (0.58) | F10 | |
| SCHEMBL5936136 | 0.86 | F10 (0.58) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235544-B2 | for use in conjunction with thrombolytic agents, thus permitting the use of a lower dose of thrombolytic agent; treatment of acute vascular diseases; may have potential in neurogenerative diseases such as Parkinson's and Alzheimer's disease | GLAXO GROUP LIMITED (GB) | 2007-06-26 | — | — | US | disclosed |
| US-7235544-B2 | for use in conjunction with thrombolytic agents, thus permitting the use of a lower dose of thrombolytic agent; treatment of acute vascular diseases; may have potential in neurogenerative diseases such as Parkinson's and Alzheimer's disease | GLAXO GROUP LIMITED (GB) | 2007-06-26 | — | — | US | disclosed |
| WO-2004110997-A1 | 3- SULFONYLAMINO- PYRROLIDINE- 2- ONE DERIVATIVES AS INHIBITORS OF FACTOR XA | GLAXO GROUP LIMITED (GB) | 2004-12-23 | — | — | WO | disclosed |