Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8297238 | 0.86 | POLB (0.53) | KMT2ATP53ALDH1A1TSHRCRHBP | |
| SCHEMBL8292747 | 0.86 | HSP90AA1 (0.55) | KMT2ATP53ALDH1A1TSHRCRHBP | |
| SCHEMBL8297964 | 0.82 | SMN1; SMN2 (0.49) | KMT2ATP53ALDH1A1TSHRCRHBP | |
| SCHEMBL8292069 | 0.81 | HSP90AA1 (0.52) | KMT2ATP53TSHRCRHBPRECQL | |
| SCHEMBL8298680 | 0.80 | HSP90AA1 (0.48) | KMT2ATP53ALDH1A1TSHRCRHBP | |
| SCHEMBL8293491 | 0.80 | PDE5A (0.53) | PKMRAB9AGAALMNA | |
| SCHEMBL8293493 | 0.80 | PDE5A (0.53) | PKMRAB9AGAALMNA | |
| SCHEMBL6940177 | 0.80 | KDM4E (0.46) | KMT2ATP53ALDH1A1CRHBPRECQL | |
| SCHEMBL6940176 | 0.80 | KDM4E (0.46) | KMT2ATP53ALDH1A1CRHBPRECQL | |
| SCHEMBL8292749 | 0.79 | KMT2A (0.48) | KMT2ATP53ALDH1A1TSHRCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5716993-A | PHOSPHODIESTERASE ENZYME INHIBITOR FOR TREATING CARDIOVASCULAR DISORDER, ANGINA PECTORIS, HYPERTENSION, ASTHMA | EISAI CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |