Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8301439 | 1.00 | HPGD (0.51) | HPGDPOLBTSHRNPSR1KDM4E | |
| SCHEMBL8301774 | 0.87 | HPGD (0.54) | HPGDPOLBTSHRNPSR1KDM4E | |
| SCHEMBL8301778 | 0.87 | HPGD (0.54) | HPGDPOLBTSHRNPSR1KDM4E | |
| SCHEMBL8293093 | 0.82 | HPGD (0.59) | HPGDPOLBTSHRNPSR1KDM4E | |
| SCHEMBL8297286 | 0.82 | HPGD (0.50) | HPGDPOLBTSHRNPSR1KDM4E | |
| SCHEMBL8291728 | 0.81 | HPGD (0.49) | HPGDPOLBTSHRNPSR1KDM4E | |
| SCHEMBL8301382 | 0.80 | MCHR1 (0.63) | HPGDPOLBTSHRKDM4EMEN1 | |
| SCHEMBL8300413 | 0.79 | MEN1 (0.58) | HPGDPOLBTSHRNPSR1KDM4E | |
| SCHEMBL8601091 | 0.79 | HPGD (0.51) | HPGDPOLBTSHRKDM4EMEN1 | |
| SCHEMBL8297193 | 0.78 | POLB (0.58) | HPGDPOLBTSHRNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |