Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.51 |
| ▸ | APP | P05067 | 4/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8298760 | 0.92 | HTR2C (0.59) | IDO1SLC6A4APPHTR2CADRB2 | |
| SCHEMBL8304104 | 0.89 | SLC6A4 (0.64) | IDO1SLC6A4HTR2AHTR1ADRD1 | |
| SCHEMBL31295107 | 0.80 | HTR2A (0.69) | IDO1SLC6A4APPHTR2CADRB2 | |
| SCHEMBL5097763 | 0.80 | HTR2A (0.69) | IDO1SLC6A4APPHTR2CADRB2 | |
| SCHEMBL2270899 | 0.80 | SLC6A4 (0.67) | SLC6A4APPHTR2CADRB2HTR2A | |
| SCHEMBL5097759 | 0.80 | HTR2A (0.69) | IDO1SLC6A4APPHTR2CADRB2 | |
| SCHEMBL28316012 | 0.80 | SLC6A4 (0.56) | IDO1SLC6A4APPHTR2CADRB2 | |
| SCHEMBL6637435 | 0.80 | IDO1 (0.58) | IDO1SLC6A4HTR2AHTR1ADRD1 | |
| Lithium Ion SCHEMBL31530810 | 0.78 | HTR2A (0.66) | IDO1SLC6A4APPHTR2CADRB2 | |
| SCHEMBL30279603 | 0.76 | HTR2C (0.81) | SLC6A4APPHTR2CADRB2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |
| EP-0898569-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GmbH (DE) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997040038-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GMBH (DE) | 1997-10-30 | — | — | WO | disclosed |