Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 12/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5017474 | 0.91 | KCNH2 (1.00) | KCNH2ALDH1A1TSHRGAALMNA | |
| SCHEMBL5024658 | 0.81 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL5026294 | 0.79 | KCNH2 (1.00) | KCNH2TSHRHTR1ADRD2DRD1 | |
| SCHEMBL5024699 | 0.77 | KCNH2 (0.72) | KCNH2TSHRHTR1ADRD2DRD1 | |
| SCHEMBL5024071 | 0.77 | KCNH2 (0.82) | KCNH2ALDH1A1GAAPOLBMAPT | |
| SCHEMBL5080746 | 0.77 | KCNH2 (0.81) | KCNH2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL5023974 | 0.76 | KCNH2 (0.81) | KCNH2TSHRLMNAHTR1ADRD2 | |
| SCHEMBL5023661 | 0.76 | KCNH2 (0.75) | KCNH2HTR1ADRD2DRD4DRD5 | |
| SCHEMBL5079870 | 0.76 | KCNH2 (1.00) | KCNH2TSHRHTR1ADRD2DRD1 | |
| SCHEMBL5023608 | 0.74 | KCNH2 (0.81) | KCNH2HTR1ADRD2DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089922-A2 | CALCIUM CHANNEL INHIBITORS COMPRISING BENZHYDRIL SPACED FROM PIPERAZINE | NEUROMED TECHNOLOGIES, INC. (CA) | 2004-10-21 | — | — | WO | disclosed |