Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HPSE | Q9Y251 | 6/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001581 | 0.84 | MAPT (0.53) | NPC1RAB9AMAPTKDM4EMEN1 | |
| SCHEMBL8304835 | 0.83 | MAPT (0.47) | ESR1ESR2NPC1RAB9AMAPT | |
| SCHEMBL8305255 | 0.83 | MAPT (0.47) | ESR1ESR2NPC1RAB9AMAPT | |
| SCHEMBL9001579 | 0.81 | MAPT (0.53) | NPC1RAB9AMAPTKDM4EMEN1 | |
| SCHEMBL8301421 | 0.81 | MAPT (0.47) | ESR1ESR2NPC1RAB9AMAPT | |
| SCHEMBL8302228 | 0.81 | MAPT (0.47) | ESR1ESR2NPC1RAB9AMAPT | |
| SCHEMBL9001595 | 0.79 | KDM4E (0.59) | ESR1ESR2NPC1RAB9AMAPT | |
| SCHEMBL8303921 | 0.79 | NPC1 (0.52) | ESR1ESR2NPC1RAB9AMAPT | |
| SCHEMBL10977878 | 0.78 | RARB (0.56) | MAPTMEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL10976220 | 0.78 | RARB (0.56) | MAPTMEN1ALDH1A1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462578-B1 | Mesomorphic compound for use in liquid crystal composition and liquid crystal device and display apparatus using same | CANON KK (JP) | 1999-09-22 | — | — | EP | disclosed |
| US-5244596-A | Benzoxazoles | CANON KABUSHIKI KAISHA (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0462578-A1 | Mesomorphic compound for use in liquid crystal composition and liquid crystal device and display apparatus using same | CANON KABUSHIKI KAISHA (JP) | 1991-12-27 | — | — | EP | disclosed |