Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16786687 | 0.88 | ATM (0.43) | ATMPRKDCADKADRA2AADRA2B | |
| SCHEMBL16787348 | 0.88 | ATM (0.43) | ATMPRKDCADKALDH1A1HSD17B10 | |
| SCHEMBL16787189 | 0.87 | ATM (0.42) | ATMPRKDCADKADRA2AADRA2B | |
| SCHEMBL16787343 | 0.87 | ATM (0.46) | ATMPRKDCADKALDH1A1HSD17B10 | |
| SCHEMBL16787164 | 0.86 | ATM (0.43) | ATMPRKDCADKALDH1A1 | |
| SCHEMBL22706337 | 0.85 | PRKDC (0.41) | ATMPRKDCADK | |
| SCHEMBL12490334 | 0.84 | ATM (0.44) | ATMPRKDCADKALDH1A1AHR | |
| SCHEMBL12488705 | 0.84 | ATM (0.44) | ATMPRKDCADK | |
| SCHEMBL12487451 | 0.82 | ATM (0.45) | ATMPRKDCADK | |
| SCHEMBL12489912 | 0.82 | PRKDC (0.43) | ATMPRKDCADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004094461-A2 | HUMAN GLUCAGON-LIKE-PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-11-04 | — | — | WO | disclosed |
| WO-2003033671-A2 | HUMAN GLUCAGON-LIKE-PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-04-24 | — | — | WO | disclosed |