Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 16/20 | 0.71 |
| ▸ | PTGS2 | P35354 | 14/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289148 | 0.87 | PTGS1 (0.67) | PTGS1PTGS2POLBTDP1HTR2C | |
| SCHEMBL14516244 | 0.87 | PTGS1 (0.79) | PTGS1PTGS2 | |
| SCHEMBL14497487 | 0.86 | PTGS1 (0.77) | PTGS1PTGS2POLBTDP1 | |
| SCHEMBL8296495 | 0.80 | PTGS1 (0.64) | PTGS1PTGS2 | |
| SCHEMBL14516168 | 0.75 | PTGS1 (0.80) | PTGS1PTGS2 | |
| SCHEMBL14516618 | 0.75 | PTGS1 (0.76) | PTGS1PTGS2 | |
| SCHEMBL8287007 | 0.75 | PTGS1 (0.65) | PTGS1PTGS2POLB | |
| SCHEMBL8295867 | 0.75 | PTGS1 (0.66) | PTGS1PTGS2 | |
| SCHEMBL8289158 | 0.74 | PTGS1 (0.64) | PTGS1PTGS2POLBTDP1 | |
| SCHEMBL14497495 | 0.73 | PTGS1 (0.76) | PTGS1PTGS2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004105699-A2 | COMPOSITIONS OF A CYCLOOXYGENASE-2 SELECTIVE INHIBITOR AND A CANNABINOID AGENT FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DAMAGE | PHARMACIA CORPORATION (US) | 2004-12-09 | — | — | WO | disclosed |