Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14440621 | 0.90 | SRD5A1 (0.45) | SRD5A1SRD5A2F10LMNAMAPT | |
| SCHEMBL8302634 | 0.86 | SRD5A1 (0.43) | SRD5A1SRD5A2F10ALDH1A1KMT2A | |
| SCHEMBL4858641 | 0.86 | SRD5A1 (0.43) | SRD5A1SRD5A2F10ALDH1A1KMT2A | |
| SCHEMBL5460656 | 0.85 | SRD5A1 (0.47) | SRD5A1SRD5A2LMNAMAPTBCHE | |
| Hydrochloric Acid SCHEMBL5467892 | 0.84 | SRD5A1 (0.46) | SRD5A1SRD5A2LMNAMAPTBCHE | |
| SCHEMBL5460647 | 0.79 | F10 (0.68) | F10 | |
| SCHEMBL5459034 | 0.78 | F10 (0.73) | F10 | |
| SCHEMBL5459037 | 0.78 | F10 (0.73) | F10 | |
| SCHEMBL5460632 | 0.77 | F10 (0.60) | F10 | |
| SCHEMBL8298647 | 0.76 | F10 (0.54) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004110434-A1 | 2-PYRROLIDONE DERIVATIVES AND USE THEREOF AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-12-23 | — | — | WO | disclosed |