Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 13/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5024012 | 0.87 | KCNH2 (0.72) | KCNH2KDM4EALDH1A1HTT | |
| SCHEMBL5026282 | 0.85 | KCNH2 (1.00) | KCNH2KDM4EALDH1A1HTT | |
| SCHEMBL5023992 | 0.85 | KCNH2 (1.00) | KCNH2KDM4EALDH1A1HTT | |
| SCHEMBL5024105 | 0.83 | KCNH2 (0.66) | KCNH2KDM4EALDH1A1HTT | |
| SCHEMBL5024627 | 0.81 | KCNH2 (0.72) | KCNH2KDM4EALDH1A1HTT | |
| SCHEMBL5026271 | 0.78 | KCNH2 (0.75) | KCNH2KDM4EALDH1A1HTT | |
| SCHEMBL5024626 | 0.78 | KCNH2 (0.66) | KCNH2KDM4EALDH1A1HTT | |
| SCHEMBL5076819 | 0.77 | KCNH2 (0.77) | KCNH2KDM4EALDH1A1HTT | |
| SCHEMBL5634676 | 0.77 | KCNH2 (1.00) | KCNH2ALDH1A1 | |
| SCHEMBL5023984 | 0.77 | KCNH2 (0.76) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089922-A2 | CALCIUM CHANNEL INHIBITORS COMPRISING BENZHYDRIL SPACED FROM PIPERAZINE | NEUROMED TECHNOLOGIES, INC. (CA) | 2004-10-21 | — | — | WO | disclosed |