SCHEMBL8303280

SCHEMBL8303280

CCN(CC)Cc1cccc(/C(O)=C/c2nc3ccc(F)cc3c(=O)n2-c2ccccc2Cl)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8160035 1.00
SCHEMBL2843974 0.85
SCHEMBL2843971 0.85
SCHEMBL8114080 0.84
SCHEMBL8114082 0.84
Hydrochloric Acid SCHEMBL1996112 0.84
Hydrochloric Acid SCHEMBL1996114 0.84
SCHEMBL8304275 0.83
Fumaric Acid SCHEMBL8301403 0.83
Maleic Acid SCHEMBL8301393 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0934934-A2 Methods of preparing substituted 3-phenyl- and 3-pyridyl-4(3H)-quinazolinones and atropisomers thereof Pfizer Products Inc. (US) 1999-08-11 EP disclosed