Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ENGASE | Q8NFI3 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.33 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303532 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2POLBL3MBTL1ENGASECHRNB2 | |
| SCHEMBL8303527 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2POLBL3MBTL1ENGASECHRNB2 | |
| SCHEMBL18587702 | 0.77 | POLB (0.37) | POLBL3MBTL1 | |
| SCHEMBL21458061 | 0.77 | POLB (0.37) | POLBL3MBTL1 | |
| SCHEMBL3564573 | 0.77 | POLB (0.37) | POLBL3MBTL1 | |
| SCHEMBL24015828 | 0.75 | DPP4 (0.37) | POLBL3MBTL1 | |
| SCHEMBL24015820 | 0.75 | DPP4 (0.37) | POLBL3MBTL1 | |
| SCHEMBL24293030 | 0.70 | CHRM2 (0.51) | SMN1; SMN2 | |
| SCHEMBL31432925 | 0.70 | CHRM2 (0.51) | SMN1; SMN2 | |
| SCHEMBL31432908 | 0.70 | CHRM2 (0.51) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607374-B1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | PO HANG IRON & STEEL (KR) | 1999-04-07 | — | — | EP | disclosed |
| US-5700817-A | Cyclic lipid derivatives as potent PAF antagonists | POHANG IRON & STEEL CO., LTD. (KR) | 1997-12-23 | — | — | US | disclosed |
| US-5610310-A | Cyclic lipid derivatives as potent PAF antagonists | POHANG IRON & STEEL CO., LTD (KR) | 1997-03-11 | — | — | US | disclosed |
| EP-0607374-A1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | POHANG IRON & STEEL CO., LTD. (KR) | 1994-07-27 | — | — | EP | disclosed |
| WO-1994000447-A1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | POHANG IRON & STEEL CO., LTD. (KR) | 1994-01-06 | — | — | WO | disclosed |